Age-Related Dry Eye Lactoferrin and Lactobionic Acid.

Abstract

Dry eye is the most prominent pathology among those involving the ocular surface: a decrease of the aqueous (less frequent) or the lipid (more frequent) component of the tear film is the cause of the diminished stability of tears that is observed in this pathology. Dry eye shows a clear distribution linked to both sex (being more frequent among women) and age (increasing with aging). Therefore, specific treatments taking into account the etiology of the disease would be desired. The role of lactoferrin and its functional mimetic lactobionic acid are reported here as a possible remedy for age-related dry eye.

• Authors: Dario Rusciano, Salvatore Pezzino, Melania Olivieri, Martina Cristaldi, Caterina Gagliano, Gabriella Lupo, Carmelina Daniela Anfuso
• Journal: Ophthalmic research (Ophthalmic Res) Vol. 60 Issue 2 Pg. 94-99 ( 2018) ISSN: 1423-0259 [Electronic] Switzerland
• PMID: 29920480 (Publication Type: Journal Article, Review)
• Copyright: © 2018 S. Karger AG, Basel.

Chemical References

• Disaccharides
• lactobionic acid
• Lactoferrin

Topics

• Disaccharides (physiology)
• Dry Eye Syndromes (metabolism)
• Humans
• Lactoferrin (physiology)
• Tears (metabolism)