Abstract | AIMS: MAIN METHODS: The effects of puerarin on mitochondrial biogenesis, oxidative phosphorylation, dynamics of fusion, fission and mitophagy, oxidative stress, as well as inflammatory response and insulin sensitivity in L6 myotubes treated with palmitate were examined. KEY FINDINGS: SIGNIFICANCE:
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Authors | Xiufang Chen, Long Yi, Shiyu Song, Lei Wang, Qiao Liang, Yong Wang, Yongzheng Wu, Qian Gao |
Journal | Life sciences
(Life Sci)
Vol. 206
Pg. 84-92
(Aug 01 2018)
ISSN: 1879-0631 [Electronic] Netherlands |
PMID | 29802940
(Publication Type: Journal Article)
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Copyright | Copyright © 2018 Elsevier Inc. All rights reserved. |
Chemical References |
- Antioxidants
- Isoflavones
- Palmitates
- puerarin
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Topics |
- Animals
- Antioxidants
(pharmacology)
- Cell Fusion
- Cell Line
- Inflammation
(prevention & control)
- Insulin Resistance
- Isoflavones
(pharmacology)
- Membrane Potential, Mitochondrial
(drug effects)
- Mitochondria, Muscle
(drug effects)
- Mitochondrial Diseases
(chemically induced, prevention & control)
- Mitophagy
(drug effects)
- Muscle Fibers, Skeletal
(drug effects, pathology)
- Oxidative Phosphorylation
(drug effects)
- Palmitates
(antagonists & inhibitors, toxicity)
- Rats
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