A Unique Preparation and Delivery Method for Acitretin for Neonatal Harlequin Ichthyosis.

Abstract

Harlequin ichthyosis is a rare form of congenital ichthyosis with a distinct phenotypic appearance. We describe a case of a newborn baby with harlequin ichthyosis who was treated with an oral formulation of acitretin. The treatment resulted in a satisfactory improvement in the skin condition of the patient. The tolerance to the drug was good with no side effects in the patient. The aim of this case report is to highlight an extemporaneous preparation of acitretin from the commonly available capsule form, which is effective for use in neonates with harlequin ichthyosis. It also highlights the risk of exposure to health care providers to acitretin.

• Authors: Kriti Damodaran, Alok Bhutada, Shantanu Rastogi
• Journal: The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG (J Pediatr Pharmacol Ther) 2018 Mar-Apr Vol. 23 Issue 2 Pg. 164-167 ISSN: 1551-6776 [Print] United States
• PMID: 29720920 (Publication Type: Case Reports)