Serum anti-müllerian hormone concentrations in reproductive age women with and without polycystic ovary syndrome: the influence of body mass index.

Abstract

PURPOSE:

To evaluate the correlation between anti-müllerian hormone (AMH) and body mass index (BMI) in patients with and without polycystic ovarian syndrome (PCOS).

METHODS:

Serum AMH levels of 332 women in their reproductive period and below 45 years of age who were admitted to our reproductive endocrinology clinic with infertility were investigated in a cross-sectional study. Patients were divided into two groups as BMI under and equal or over 25 kg/m2. Both groups were divided into two subgroups as PCOS and non-PCOS. AMH levels of patients were analyzed for each group.

RESULTS:

Mean AMH values of BMI <25 and ≥25 kg/m2 groups were 3.87 ± 2.95 and 3.58 ± 2.93 ng/mL, respectively (P > 0.05) in all patients. Means of AMH were not significantly different in BMI quartiles (r = -0.008401, P = 0.96). Among 107 patients with PCOS, means of AMH were 6.85 ± 2.95 ng/mL in 56 patients with BMI <25 kg/m2 and 6.66 ± 3.18 ng/mL in 51 patients with BMI ≥25 kg/m2 (P > 0.05). In the group of 225 non-PCOS patients, means of AMH were 2.27 ± 1.12 ng/mL in 104 patients with BMI <25 kg/m2 and 2.28 ± 1.49 ng/mL in 121 patients with BMI ≥25 kg/m2 (P > 0.05).

CONCLUSIONS:

Body mass index does not seem to have an effect on serum AMH levels in reproductive age women both with and without PCOS.

• Authors: Sezai Sahmay, Onur Guralp, Levent M Senturk, Metehan Imamoglu, Mustafa Kucuk, Tulay Irez
• Journal: Reproductive medicine and biology (Reprod Med Biol) Vol. 10 Issue 2 Pg. 113-120 (Jun 2011) ISSN: 1445-5781 [Print] Japan
• PMID: 29699087 (Publication Type: Journal Article)