Monopolar Transurethral Enucleo-Resection of the Prostate Versus Holmium Laser Enucleation of the Prostate: A Canadian Novel Experience.

Abstract

OBJECTIVE:

To study the functional outcome of patients undergoing transurethral enucleation and resection of the prostate (TUERP) vs patients undergoing holmium laser enucleation of the prostate (HoLEP) in men with bladder outlet obstruction.

MATERIALS AND METHODS:

We retrospectively analyzed our prospectively collected database of two groups of patients. Twenty-four patients underwent TUERP (group 1), and 27 underwent HoLEP (group 2). Preoperative characteristics, intervention parameters, postoperative functional outcomes, uroflowmetry, and complications were collected.

RESULTS:

Mean prostate size in groups 1 and 2 were 87.2 and 93.5 cc, respectively. The mean duration of surgery was 110 minutes in group 1 and 136 minutes in group 2. In group 1, prostate-specific antigen (PSA) dropped from 4.4 to 1.2 ng/cc after 12 months. International Prostate Symptom Score (IPSS) was 3.75 at 12 months with a preoperative value of 20.9. With respect to maximum urinary flow rate (Qmax), it increased to 21.8 mL/s from a preoperative value of 6.4 mL/s. In group 2, the PSA dropped from 7.6 to 1.3 ng/cc. IPSS dropped from 22.3 to 3.8, Qmax increased from 7.7 to 22.5 mL/s. Hemoglobin, complications, and all studied parameters were not statistically significant between both groups.

CONCLUSION:

In this study, TUERP was safe and efficacious in benign prostatic hyperplasia patients with large glands. Modifications can be implemented on the standard transurethral resection of the prostate technique to treat patients with prostate sizes >70 cc.

• Authors: Khaled Ajib, Joseph Zgheib, Noura Salibi, Marc Zanaty, Mila Mansour, Abdullah Alenizi, Assaad El-Hakim
• Journal: Journal of endourology (J Endourol) Vol. 32 Issue 6 Pg. 509-515 (06 2018) ISSN: 1557-900X [Electronic] United States
• PMID: 29641356 (Publication Type: Journal Article)

Chemical References

• Biomarkers
• Prostate-Specific Antigen
• Holmium

Topics

• Aged
• Biomarkers (analysis)
• Canada
• Holmium (therapeutic use)
• Humans
• Laser Therapy (methods)
• Lasers, Solid-State (adverse effects, therapeutic use)
• Male
• Middle Aged
• Prostate-Specific Antigen (analysis)
• Prostatic Hyperplasia (surgery)
• Quality of Life
• Retrospective Studies
• Transurethral Resection of Prostate (methods)
• Urinary Bladder Neck Obstruction (etiology, surgery)