Abstract | OBJECTIVES: METHODS: RESULTS: CONCLUSION:
Haemolysis in patients with HS occurred because the fragile proteins in erythrocytes (band 3, spectrin, and ankyrin) collapsed due to compression during blood circulation in the spleen. Further, haemolysis in patients with haemoglobinopathy occurred owing to membrane damage due to combined spectrin, band 3 with denatured haemoglobin in the vessel during blood circulation.
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Authors | Atsushi Shibuya, Hiroaki Kawashima, Masato Tanaka |
Journal | Hematology (Amsterdam, Netherlands)
(Hematology)
Vol. 23
Issue 9
Pg. 669-675
(Oct 2018)
ISSN: 1607-8454 [Electronic] England |
PMID | 29623813
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adolescent
- Adult
- Child
- Child, Preschool
- Erythrocyte Membrane
(metabolism, pathology)
- Female
- Hemolysis
- Humans
- Male
- Membrane Proteins
(metabolism)
- Spherocytosis, Hereditary
(metabolism, pathology)
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