Noninvasive neuromodulation in migraine and cluster headache.

Abstract

PURPOSE OF REVIEW:

The purpose of this narrative review is to provide an overview of the currently available noninvasive neuromodulation devices for the treatment of migraine and cluster headache.

RECENT FINDINGS:

Over the last decade, several noninvasive devices have undergone development and clinical trials to evaluate efficacy and safety. Based on this body of work, single-pulse transcranial magnetic stimulation, transcutaneous supraorbital neurostimulation, and noninvasive vagal nerve stimulation devices have been cleared by the United States Food and Drug Administration and are available for clinical use for the treatment of primary headache disorders.

SUMMARY:

Overall, these novel noninvasive devices appear to be safe, well tolerated, and have demonstrated promising results in clinical trials in both migraine and cluster headache. This narrative review will provide a summary and update of the proposed mechanisms of action, evidence, safety, and future directions of various currently available modalities of noninvasive neuromodulation for the treatment of migraine and cluster headache.

• Authors: Amaal Starling
• Journal: Current opinion in neurology (Curr Opin Neurol) Vol. 31 Issue 3 Pg. 268-273 (06 2018) ISSN: 1473-6551 [Electronic] England
• PMID: 29601305 (Publication Type: Journal Article, Review)

Topics

• Cluster Headache (therapy)
• Humans
• Migraine Disorders (therapy)
• Transcranial Magnetic Stimulation (methods)
• Transcutaneous Electric Nerve Stimulation (methods)
• Treatment Outcome