Urogenital anomalies and urinary incontinence in an English Cocker Spaniel dog with XX sex reversal.

Abstract

A 3-year-old dog weighing 8 kg was referred with a disorder of sexual development and persistent urinary incontinence before and after gonadohysterectomy performed at a local animal hospital. Histopathological examination disclosed hypoplasia of the testes, epididymis, pampiniform plexus, and uterus. On ultrasonography, an anomalous structure containing anechoic fluid was identified in the region dorsal to the urinary bladder. An anomalous communication between the proximal urethra and the remnant uterus and vagina was found on retrograde urethrography under fluoroscopy. Reflux of contrast medium into the anomalous structure, suspected to be the uterus and cranial vagina, from the urethra was detected. Computed tomography identified the anomalous structure between the rectum and urethra. The anomalous structure was removed via laparotomy and the urinary incontinence resolved. The diagnosis of XX sex reversal with a developmental anomaly of the genitourinary tract was made on the basis of laparotomy findings and cytogenetic and SRY gene analyses.

• Authors: Hakyoung Yoon, Sung-Hee Han, Jaehwan Kim, Kihoon Kim, Kidong Eom
• Journal: Journal of veterinary internal medicine (J Vet Intern Med) Vol. 32 Issue 3 Pg. 1166-1171 (May 2018) ISSN: 1939-1676 [Electronic] United States
• PMID: 29572943 (Publication Type: Case Reports)
• Copyright: Copyright © 2018 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine.

Topics

• 46, XX Testicular Disorders of Sex Development (pathology, veterinary)
• Animals
• Clitoris (pathology)
• Dog Diseases (pathology)
• Dogs
• Epididymis (pathology)
• Female
• Male
• Testis (pathology)
• Urinary Incontinence (pathology, veterinary)
• Urogenital Abnormalities (pathology, veterinary)
• Uterus (pathology)
• Vulva (pathology)