Lumbar Osteophyte Avid on 68Ga-Prostate-Specific Membrane Antigen PET/CT.

Abstract

A 75-year-old man with recently diagnosed high-risk prostate cancer was referred for primary staging with Ga-prostate-specific membrane antigen (PSMA) PET/CT. The scan revealed intense Ga-PSMA uptake in a lumbar osteophyte on the right side of level L2/L3, whereas several other spinal osteophytes showed no Ga-PSMA uptake. MRI findings in the L3 vertebra was consistent with a benign Modic type 1 lesion, but MRI showed no signs of malignancy in the osteophyte with high Ga-PMSA uptake. This case presents an osteophyte as an addition to the list of potential benign pitfalls to be aware of when interpreting Ga-PSMA PET/CT.

• Authors: Mads Ryø Jochumsen, Michael Alle Madsen, Lise Gammelgaard, Kirsten Bouchelouche
• Journal: Clinical nuclear medicine (Clin Nucl Med) Vol. 43 Issue 6 Pg. 456-457 (Jun 2018) ISSN: 1536-0229 [Electronic] United States
• PMID: 29538033 (Publication Type: Case Reports, Journal Article)

Chemical References

• Gallium Isotopes
• Gallium Radioisotopes
• Oligopeptides
• Radiopharmaceuticals
• gallium 68 PSMA-11
• Edetic Acid

Topics

• Aged
• Edetic Acid (analogs & derivatives)
• Gallium Isotopes
• Gallium Radioisotopes
• Humans
• Lumbar Vertebrae (diagnostic imaging)
• Magnetic Resonance Imaging
• Male
• Oligopeptides
• Osteophyte (diagnostic imaging)
• Positron Emission Tomography Computed Tomography
• Prostatic Neoplasms (diagnostic imaging)
• Radiopharmaceuticals