Consumption of sugar-sweetened and artificially sweetened soft drinks and risk of obesity-related cancers.

Abstract

OBJECTIVE:

To test the hypothesis that more frequent consumption of sugar-sweetened soft drinks would be associated with increased risk of obesity-related cancers. Associations for artificially sweetened soft drinks were assessed for comparison.

DESIGN:

Prospective cohort study with cancers identified by linkage to cancer registries. At baseline, participants completed a 121-item FFQ including separate questions about the number of times in the past year they had consumed sugar-sweetened or artificially sweetened soft drinks. Anthropometric measurements, including waist circumference, were taken and questions about smoking, leisure-time physical activity and intake of alcoholic beverages were completed.

SETTING:

The Melbourne Collaborative Cohort Study (MCCS) is a prospective cohort study which recruited 41 514 men and women aged 40-69 years between 1990 and 1994. A second wave of data collection occurred in 2003-2007.

SUBJECTS:

Data for 35 593 participants who developed 3283 incident obesity-related cancers were included in the main analysis.

RESULTS:

Increasing frequency of consumption of both sugar-sweetened and artificially sweetened soft drinks was associated with greater waist circumference at baseline. For sugar-sweetened soft drinks, the hazard ratio (HR) for obesity-related cancers increased as frequency of consumption increased (HR for consumption >1/d v. 1/d v. <1/month=1·00; 95 % CI 0·79, 1·27; P-trend=0·61).

CONCLUSIONS:

Our results add to the justification to minimise intake of sugar-sweetened soft drinks.

• Authors: Allison M Hodge, Julie K Bassett, Roger L Milne, Dallas R English, Graham G Giles
• Journal: Public health nutrition (Public Health Nutr) Vol. 21 Issue 9 Pg. 1618-1626 (06 2018) ISSN: 1475-2727 [Electronic] England
• PMID: 29463332 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Dietary Sugars
• Sweetening Agents

Topics

• Adult
• Aged
• Australia (epidemiology)
• Beverages (adverse effects, analysis)
• Diet Surveys
• Dietary Sugars (adverse effects, analysis)
• Female
• Humans
• Male
• Middle Aged
• Neoplasms (epidemiology, etiology)
• Obesity (complications)
• Prospective Studies
• Risk Factors
• Sweetening Agents (adverse effects, analysis)