Abstract | OBJECTIVE: MATERIALS & METHODS: This study was performed according to the PRISMA and MOOSE guidelines. Eligible studies were identified through a comprehensive search of PubMed, Scopus and Cochrane Central until July 20, 2017. A meta-analysis of random effects model was conducted. The I-square statistic was used to assess for heterogeneity. RESULTS: Five studies and 143 patients were included. Periprocedural stroke, myocardial infarction (MI) and death rates were similar between the two revascularization approaches. However, the risk for cranial nerve (CN) injury was higher in the CEA group (OR: 7.09; 95% CI: 1.17-42.88; I2 = 0%). CEA was associated with lower mortality rates after a mean follow-up of 50 months (OR: 0.29; 95% CI: 0.09-0.97; I2 = 0%). No difference was identified in long-term restenosis rates between CEA and CAS. CONCLUSIONS: Patients with radiation-induced carotid artery stenosis can safely undergo both CAS and CEA with similar risks of periprocedural stroke, MI and death. However, patients treated with CEA have a higher risk for periprocedural CN injuries and a lower risk for long-term mortality.
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Authors | Stefanos Giannopoulos, Pavlos Texakalidis, Anil Kumar Jonnalagadda, Theofilos Karasavvidis, Spyridon Giannopoulos, Damianos G Kokkinidis |
Journal | Cardiovascular revascularization medicine : including molecular interventions
(Cardiovasc Revasc Med)
2018 Jul - Aug
Vol. 19
Issue 5 Pt B
Pg. 638-644
ISSN: 1878-0938 [Electronic] United States |
PMID | 29422277
(Publication Type: Journal Article, Meta-Analysis, Systematic Review)
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Copyright | Copyright © 2018. Published by Elsevier Inc. |
Topics |
- Aged
- Carotid Stenosis
(diagnostic imaging, etiology, mortality, surgery)
- Endarterectomy, Carotid
(adverse effects, mortality)
- Endovascular Procedures
(adverse effects, instrumentation, mortality)
- Female
- Head and Neck Neoplasms
(radiotherapy)
- Humans
- Male
- Middle Aged
- Postoperative Complications
(etiology)
- Radiation Injuries
(diagnostic imaging, etiology, mortality, surgery)
- Radiotherapy
(adverse effects)
- Risk Assessment
- Risk Factors
- Stents
- Treatment Outcome
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