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Unsatisfactory efficacy in randomized study of reduced-dose CPX-351 for medically less fit adults with newly diagnosed acute myeloid leukemia or other high-grade myeloid neoplasm.

AuthorsRoland B Walter, Megan Othus, Kaysey F Orlowski, Emily N McDaniel, Bart L Scott, Pamela S Becker, Mary-Elizabeth M Percival, Paul C Hendrie, Bruno C Medeiros, Michael T Chiarella, Arthur C Louie, Elihu H Estey
JournalHaematologica (Haematologica) Vol. 103 Issue 3 Pg. e106-e109 (03 2018) ISSN: 1592-8721 [Electronic] Italy
PMID29242304 (Publication Type: Clinical Trial, Phase II, Letter, Randomized Controlled Trial, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
Chemical References
  • CPX-351
  • Cytarabine
  • Daunorubicin
Topics
  • Adult
  • Aged
  • Aged, 80 and over
  • Cytarabine (administration & dosage)
  • Daunorubicin (administration & dosage)
  • Female
  • Humans
  • Leukemia, Myeloid (drug therapy, mortality)
  • Leukemia, Myeloid, Acute (drug therapy, mortality)
  • Male
  • Middle Aged
  • Physical Fitness
  • Survival Analysis
  • Treatment Outcome

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