Abstract | BACKGROUND: METHODS: RESULTS: Average diet quality was moderate to poor, with mean scores of 43 (DASH, range 0-80), 55 (HEI2010, range 0-100), 3.7 (mKIDMED, range 3-12) and 7237 (TAC). None of the four diet quality scores was associated with the selected biomarkers of inflammation in any analyses. Evaluation of a non-linear relationship or interactions with BMI or levels of glycemic control did not alter the findings. Replication of analyses using longitudinal data yielded consistent findings with our cross-sectional results. CONCLUSIONS:
Biomarkers of inflammation in youth with T1D may not be directly influenced by dietary intake, at least at the levels of dietary quality observed here. More work is needed to understand what physiologic mechanisms specific to persons with T1D might inhibit the generally beneficial influence of high dietary quality on systemic inflammation observed in populations without diabetes.
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Authors | Angela D Liese, Xiaonan Ma, Xiaoguang Ma, Murray A Mittleman, Natalie S The, Debra A Standiford, Jean M Lawrence, Catherine Pihoker, Santica M Marcovina, Elizabeth J Mayer-Davis, Robin C Puett |
Journal | Journal of diabetes and its complications
(J Diabetes Complications)
Vol. 32
Issue 2
Pg. 179-184
(02 2018)
ISSN: 1873-460X [Electronic] United States |
PMID | 29198994
(Publication Type: Journal Article, Multicenter Study, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)
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Copyright | Copyright © 2017 Elsevier Inc. All rights reserved. |
Chemical References |
- Antioxidants
- Biomarkers
- C-Reactive Protein
|
Topics |
- Adolescent
- Antioxidants
(metabolism)
- Biomarkers
(blood)
- C-Reactive Protein
(metabolism)
- Child
- Diabetes Mellitus, Type 1
(blood, epidemiology)
- Diet
(statistics & numerical data)
- Diet Surveys
- Feeding Behavior
(physiology)
- Female
- Humans
- Inflammation
(blood)
- Male
- Nutritive Value
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