Multitargeted Feeding Strategies Improve Nutrition Outcome and Are Associated With Reduced Pneumonia in a Level 1 Trauma Intensive Care Unit.

Abstract

BACKGROUND:

Factors impeding delivery of adequate enteral nutrition (EN) to trauma patients include delayed EN initiation, frequent surgeries and procedures, and postoperative ileus. We employed 3 feeding strategies to optimize EN delivery: (1) early EN initiation, (2) preoperative no nil per os feeding protocol, and (3) a catch-up feeding protocol. This study compared nutrition adequacy and clinical outcomes before and after implementation of these feeding strategies.

METHODS:

All trauma patients aged ≥18 years requiring mechanical ventilation for ≥7 days and receiving EN were included. Patients who sustained nonsurvivable injuries, received parenteral nutrition, or were readmitted to the intensive care unit (ICU) were excluded. EN data were collected until patients received an oral diet or were discharged from the ICU. The improvement was quantified by comparing nutrition adequacy and outcomes between April 2014-May 2015 (intervention) and May 2012-June 2013 (baseline).

RESULTS:

The intervention group (n = 118) received significantly more calories (94% vs 75%, P < .001) and protein (104% vs 74%, P < .001) than the baseline group (n = 121). The percentage of patients receiving EN within 24 and 48 hours of ICU admission increased from 41% to 70% and from 79% to 96% respectively after intervention (P < .001). Although there were fewer 28-ay ventilator-free days in the intervention group than in the baseline group (12 vs 16 days, P = .03), receipt of the intervention was associated with a significant reduction in pneumonia (odds ratio, 0.53; 95% confidence interval, 0.31-0.89; P = .017) after adjusting sex and Injury Severity Score.

CONCLUSIONS:

Implementation of multitargeted feeding strategies resulted in a significant increase in nutrition adequacy and a significant reduction in pneumonia.

• Authors: Jenny C Lee, George W Williams, Rosemary A Kozar, Lillian S Kao, Krislynn M Mueck, Andrew D Emerald, Natacha C Villegas, Laura J Moore
• Journal: JPEN. Journal of parenteral and enteral nutrition (JPEN J Parenter Enteral Nutr) Vol. 42 Issue 3 Pg. 529-537 (Mar 2018) ISSN: 1941-2444 [Electronic] United States
• PMID: 29187048 (Publication Type: Journal Article)
• Copyright: © 2017 American Society for Parenteral and Enteral Nutrition.

Chemical References

• Dietary Proteins

Topics

• Adolescent
• Adult
• Dietary Proteins (administration & dosage)
• Energy Intake
• Enteral Nutrition (methods)
• Female
• Humans
• Intensive Care Units
• Length of Stay
• Male
• Middle Aged
• Nutritional Status
• Pneumonia (prevention & control)
• Respiration, Artificial
• Time Factors
• Trauma Centers
• Treatment Outcome
• Wounds and Injuries (therapy)