Obesity, which is associated with dietary habits, has become a global social problem and causes many
metabolic diseases. In China, both percentages of adult
obesity and
overweight are far lower compared to western countries. It was designed to increase the two levels of daily intake in human, namely 3.8% and 6.5%, which are recommendatory intake (25 g/d) and Chinese citizens' practical intake (41.4 g/d), respectively. The mice were respectively fed with feeds added with
soybean oil,
lard or the oil blended by both for 12 weeks. In the mice fed with diet containing 3.8% of the three
oils or 6.5% blended oil, their
body weight, body fat rate, cross-sectional area of adipocytes, adipogenesis and lipogenesis in adipose were decreased, whereas hydrolysis of triglyserides in adipose was increased. This study demonstrated that the oil mixture containing
lard and
soybean oil had a remarkable anti-
obesity effect. It suggests that the traditional Chinese dietary habits using
oils blended with
lard and
soybean oil, might be one of the factors of lower percentages of
overweight and
obesity in China, and that the increasing of
dietary oil intake and the changing of its component resulted in the increasing of
obesity rate in China over the past decades.