Abstract | OBJECTIVE: To investigate the clinical characteristics of patients with uncommon distal symmetric painful small-fiber neuropathy (DSPSFN). METHODS: From September 2012 to September 2014, participants between 18-70 years of age that had DSPSFN defined by clinical signs/symptoms and ID pain > 2 or DN4 > 4 on questionnaires for more than 1 month were included. Participants who had previous historical or laboratory evidence of common etiologies of DSPSFN were excluded. Enzyme activity and genetic studies for Fabry diseaseand familial amyloid polyneuropathy were performed after participants fulfilled the inclusion and exclusion criteria. The cryoglobulin test, autoantibodies studies and electrophysiological studies were performed in these participants. RESULTS: CONCLUSIONS:
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Authors | Jung-Lung Hsu, Ming-Feng Liao, Hui-Ching Hsu, Yi-Ching Weng, Ai-Lun Lo, Kuo-Hsuan Chang, Hong-Shiu Chang, Hung-Chou Kuo, Chin-Chang Huang, Long-Sun Ro |
Journal | PloS one
(PLoS One)
Vol. 12
Issue 9
Pg. e0183948
( 2017)
ISSN: 1932-6203 [Electronic] United States |
PMID | 28957343
(Publication Type: Journal Article, Observational Study)
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Chemical References |
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Topics |
- Autoantibodies
(immunology)
- Cryoglobulinemia
(complications)
- Demography
- Electrophysiological Phenomena
- Female
- Humans
- Male
- Middle Aged
- Prospective Studies
- Small Fiber Neuropathy
(complications, diagnosis, immunology, physiopathology)
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