Abstract |
The encephalopathy that occurs in association with hemolytic uremic syndrome (HUS), which is caused by enterohemorrhagic Escherichia coli (E. coli), has a high mortality rate and patients sometimes present sequelae. We herein describe the case of a 20-year-old woman who developed encephalopathy during the convalescent stage of HUS caused by E.coli O26. Hyperintense lesions were detected in the pons, basal ganglia, and cortex on diffusion-weighted brain MRI. From the onset of HUS encephalopathy, we treated the patient with methylprednisolone (mPSL) pulse therapy alone. Her condition improved, and she did not present sequelae. Our study shows that corticosteroids appear to be effective for the treatment of some patients with HUS encephalopathy.
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Authors | Takashi Hosaka, Kiyotaka Nakamagoe, Akira Tamaoka |
Journal | Internal medicine (Tokyo, Japan)
(Intern Med)
Vol. 56
Issue 21
Pg. 2937-2941
(Nov 01 2017)
ISSN: 1349-7235 [Electronic] Japan |
PMID | 28943538
(Publication Type: Case Reports, Journal Article)
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Chemical References |
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Topics |
- Adrenal Cortex Hormones
(therapeutic use)
- Brain
(pathology)
- Brain Diseases
(complications)
- Enterohemorrhagic Escherichia coli
- Escherichia coli Infections
(complications)
- Female
- Hemolytic-Uremic Syndrome
(complications, drug therapy, etiology)
- Humans
- Young Adult
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