Abstract | OBJECTIVES: MATERIALS AND METHODS: A total of 57 053 Danish men and women aged 50-64 years participating in the Diet, Cancer and Health cohort had an adipose tissue biopsy taken at baseline, and this was analysed for saturated fatty acids content by gas chromatography. Follow-up was registry based and in this case-cohort study we used all cases and a randomly drawn subcohort of 3500 participants representative for the entire cohort. RESULTS: Data were analysed using weighted Cox proportional hazards regression. During a median follow-up of 14.6 years, a total of 4722 cases of incident atrial fibrillation were diagnosed. For both men and women, no association between adipose tissue content of total saturated fatty acids and the risk of atrial fibrillation could be demonstrated. CONCLUSION:
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Authors | Pia T Dinesen, Thomas A Rix, Albert M Joensen, Anne Tjønneland, Søren Lundbye-Christensen, Kim Overvad, Erik B Schmidt |
Journal | European journal of clinical investigation
(Eur J Clin Invest)
Vol. 47
Issue 12
(Dec 2017)
ISSN: 1365-2362 [Electronic] England |
PMID | 28906545
(Publication Type: Journal Article)
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Copyright | © 2017 Stichting European Society for Clinical Investigation Journal Foundation. |
Chemical References |
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Topics |
- Adipose Tissue
(metabolism)
- Aged
- Atrial Fibrillation
(epidemiology)
- Case-Control Studies
- Chromatography, Gas
- Cohort Studies
- Denmark
(epidemiology)
- Fatty Acids
(metabolism)
- Female
- Humans
- Incidence
- Male
- Middle Aged
- Proportional Hazards Models
- Registries
- Risk Factors
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