Abstract | OBJECTIVE: PATIENTS AND METHODS: Retrospectively, breast cancer patients with bone metastasis were included. BM metastasis was considered if the lesion was PET positive/CT occult while bone metastasis was considered if the lesion was PET positive/ CT positive. BM metastases were observed sequentially on F18-FDG PET/CT. RESULTS: CONCLUSION: This retrospective study showed clinically by 18F-FDG PET/CT imaging that BM metastasis is an early stage of bone metastasis in breast cancer. Interestingly, 18F-FDG-PET/CT showed that early eradication of individual BM metastasis by systemic treatment precluded development of bone metastasis. However, more research is needed to study the impact of an early diagnosis of BM metastases on treatment outcome.
|
Authors | Kusai M Al-Muqbel |
Journal | BioMed research international
(Biomed Res Int)
Vol. 2017
Pg. 9852632
( 2017)
ISSN: 2314-6141 [Electronic] United States |
PMID | 28884133
(Publication Type: Journal Article)
|
Chemical References |
|
Topics |
- Adult
- Aged
- Bone Marrow Cells
(pathology)
- Bone Neoplasms
(diagnosis, diagnostic imaging, pathology, secondary)
- Breast Neoplasms
(diagnosis, diagnostic imaging, pathology)
- Female
- Fluorodeoxyglucose F18
(therapeutic use)
- Humans
- Middle Aged
- Neoplasm Metastasis
- Neoplasm Staging
- Positron Emission Tomography Computed Tomography
- Radionuclide Imaging
|