The Healthy Hearts and Kidneys (HHK) study: Design of a 2×2 RCT of technology-supported self-monitoring and social cognitive theory-based counseling to engage overweight people with diabetes and chronic kidney disease in multiple lifestyle changes.

Abstract

Patients with complex chronic diseases usually must make multiple lifestyle changes to limit and manage their conditions. Numerous studies have shown that education alone is insufficient for engaging people in lifestyle behavior change, and that theory-based behavioral approaches also are necessary. However, even the most motivated individual may have difficulty with making lifestyle changes because of the information complexity associated with multiple behavior changes. The goal of the current Healthy Hearts and Kidneys study was to evaluate, different mobile health (mHealth)-delivered intervention approaches for engaging individuals with type 2 diabetes (T2D) and concurrent chronic kidney disease (CKD) in behavior changes. Participants were randomized to 1 of 4 groups, receiving: (1) a behavioral counseling, (2) technology-based self-monitoring to reduce information complexity, (3) combined behavioral counseling and technology-based self-monitoring, or (4) baseline advice. We will determine the impact of randomization assignment on weight loss success and 24-hour urinary excretion of sodium and phosphorus. With this report we describe the study design, methods, and approaches used to assure information security for this ongoing clinical trial. Clinical Trials.gov Identifier: NCT02276742.

• Authors: Mary Ann Sevick, Kathleen Woolf, Aditya Mattoo, Stuart D Katz, Huilin Li, David E St-Jules, Ram Jagannathan, Lu Hu, Mary Lou Pompeii, Lisa Ganguzza, Zhi Li, Alex Sierra, Stephen K Williams, David S Goldfarb
• Journal: Contemporary clinical trials (Contemp Clin Trials) Vol. 64 Pg. 265-273 (01 2018) ISSN: 1559-2030 [Electronic] United States
• PMID: 28867396 (Publication Type: Journal Article, Randomized Controlled Trial, Research Support, N.I.H., Extramural)
• Copyright: Copyright © 2017. Published by Elsevier Inc.

Chemical References

• Lipids
• Phosphorus, Dietary
• Sodium, Dietary
• Penicillin G

Topics

• Adult
• Aged
• Behavior Therapy
• Blood Pressure
• Body Composition
• Computers, Handheld
• Diabetes Mellitus, Type 2 (epidemiology, therapy)
• Diet
• Exercise
• Female
• Health Behavior
• Humans
• Life Style
• Lipids (blood)
• Longitudinal Studies
• Male
• Middle Aged
• Overweight (epidemiology, therapy)
• Patient Education as Topic
• Penicillin G
• Phosphorus, Dietary
• Renal Insufficiency, Chronic (epidemiology, therapy)
• Research Design
• Self Care
• Self Efficacy
• Sodium, Dietary
• Telemedicine (methods)
• Weight Reduction Programs (methods)