Establishing Clinical Cutoffs for Response and Remission on the Screen for Child Anxiety Related Emotional Disorders (SCARED).

Abstract

OBJECTIVE:

To determine optimal percent reduction and raw score cutoffs on the parent- and child-report Screen for Child Anxiety Related Emotional Disorders (SCARED) for predicting treatment response and remission among youth with anxiety disorders.

METHOD:

Data were obtained from youth (N = 438; 7-17 years old) who completed treatment in the Child/Adolescent Anxiety Multimodal treatment Study, a multisite, randomized clinical trial that examined the relative efficacy of medication (sertraline), cognitive-behavioral therapy (Coping Cat), their combination, and pill placebo for the treatment of separation anxiety disorder, generalized anxiety disorder, and social phobia. The parent- and youth-report SCARED were administered at pre- and posttreatment. Quality receiver operating characteristic methods evaluated the performance of various SCARED percent reduction and absolute cutoff scores in predicting treatment response and remission, as defined by posttreatment ratings on the Clinical Global Impression scales and the Anxiety Disorders Interview Schedule.

RESULTS:

Reductions of 55% on the SCARED-Parent and 50% on the SCARED-Youth optimally predicted treatment response. Posttreatment absolute raw scores of 10 (SCARED-Parent) and 12 (SCARED-Youth) optimally predicted remission in the total sample, although separate SCARED-Parent cutoffs for children (12-13) and adolescents (9) showed greatest quality of efficiency. Each cutoff significantly predicted response and remission at 6-month follow-up.

CONCLUSION:

Results serve as guidelines for operationalizing treatment response and remission on the SCARED, which could help clinicians systematically monitor treatment outcomes of youth with anxiety disorders in a cost- and time-efficient manner. Clinical trial registration information-Child and Adolescent Anxiety Disorders (CAMS); http://clinicaltrials.gov/; NCT00052078.

• Authors: Nicole E Caporino, Dara Sakolsky, Douglas M Brodman, Joseph F McGuire, John Piacentini, Tara S Peris, Golda S Ginsburg, John T Walkup, Satish Iyengar, Philip C Kendall, Boris Birmaher
• Journal: Journal of the American Academy of Child and Adolescent Psychiatry (J Am Acad Child Adolesc Psychiatry) Vol. 56 Issue 8 Pg. 696-702 (Aug 2017) ISSN: 1527-5418 [Electronic] United States
• PMID: 28735699 (Publication Type: Journal Article, Randomized Controlled Trial)
• Copyright: Copyright © 2017 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.

Chemical References

• Serotonin Uptake Inhibitors
• Sertraline

Topics

• Adolescent
• Anxiety Disorders (drug therapy, therapy)
• Anxiety, Separation (therapy)
• Child
• Cognitive Behavioral Therapy (methods)
• Drug Therapy, Combination
• Female
• Humans
• Male
• Outcome Assessment, Health Care (methods)
• Phobia, Social (therapy)
• Remission Induction
• Selective Serotonin Reuptake Inhibitors (pharmacology)
• Sertraline (pharmacology)