HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

An overview on biological functions and emerging therapeutic roles of apelin in diabetes mellitus.

Abstract
Type 2 diabetes mellitus is a common type of diabetes and considered as multifactorial disease. Apelin is an adipokine which secreted from white adipose tissue and involved in various functions such as insulin sensitivity and food intake. Many studies showed that apelin has a crucial role in diabetes and its concentration will change in relation with insulin resistance. In this review, we will discuss the roles of apelin in energy metabolism and pathogenesis of diabetes and explain why apelin can be a good candidate adipokine to promoting insulin sensitivity.
AuthorsFarzaneh Ghafarian Alipour, Mohamad Reza Ashoori, Younes Pilehvar-Soltanahmadi, Nosratollah Zarghami
JournalDiabetes & metabolic syndrome (Diabetes Metab Syndr) Vol. 11 Suppl 2 Pg. S919-S923 (Dec 2017) ISSN: 1878-0334 [Electronic] Netherlands
PMID28712823 (Publication Type: Journal Article, Review)
CopyrightCopyright © 2017 Diabetes India. Published by Elsevier Ltd. All rights reserved.
Chemical References
  • Apelin
  • Apelin Receptors
Topics
  • Animals
  • Apelin (physiology)
  • Apelin Receptors (physiology)
  • Diabetes Mellitus (drug therapy, etiology, metabolism)
  • Diabetic Nephropathies (etiology)
  • Diabetic Retinopathy (etiology)
  • Energy Metabolism
  • Humans
  • Insulin Resistance

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: