[Effect of tobanum on various functions of the heart in patients with ischemic heart disease and prospects for its clinical application].

Abstract

In coronary patients with relatively intact myocardial function, tobanum increases physical stress tolerance and produces positive central hemodynamic shifts, while myocardial contractility is depressed insignificantly. In patients with low myocardial functional reserve, these parameters, on the contrary, deteriorate, particularly during exercise. Combined use of tobanum and corinfar in patients with impaired myocardial contractility controls cardio- and hemodynamic shifts and increases physical stress tolerance.

• Authors: N B Gambashidze, S G Kobaladze, B Sh Burdiashvili, N L Kikodze, G T Mamaladze
• Journal: Kardiologiia (Kardiologiia) Vol. 25 Issue 9 Pg. 77-9 (Sep 1985) ISSN: 0022-9040 [Print] Russia (Federation)
• Vernacular Title: Vliianie tobanuma na nekotorye funktsii serdtsa u bol'nykh ishemicheskoĭ bolezn'iu serdtsa i perspektivy ego klinicheskogo primeneniia.
• PMID: 2867245 (Publication Type: English Abstract, Journal Article)

Chemical References

• Adrenergic beta-Antagonists
• Propanolamines
• Nifedipine
• tobanum

Topics

• Adrenergic beta-Antagonists (therapeutic use)
• Adult
• Coronary Disease (drug therapy, physiopathology)
• Drug Therapy, Combination
• Heart (physiopathology)
• Hemodynamics
• Humans
• Middle Aged
• Myocardial Contraction
• Nifedipine (administration & dosage)
• Physical Exertion
• Propanolamines (administration & dosage, therapeutic use)