Abstract | BACKGROUND: OBJECTIVES: PATIENTS AND METHODS: Between 2010 and 2016, we treated 7 children with prenatally diagnosed ARPKD. All had a planned delivery by cesarean section. After birth, oscillated ventilation with nitrogen enrichment was initiated to achieve maximum oxygenation and to decrease pumonary hypertension. All children had bilateral massive kidney hyperplasia (length 13-16 cm). RESULTS: CONCLUSIONS: Early bilateral nephrectomy in neonatal ARPKD is feasible, but requires distinctive care at a pediatric intensive care unit and a high amount of organizational efforts to treat these children adequately in the first few days. In our experience, the procedure is a promising approach to improve ventilation and enable dialysis. However, kidney transplantation, best from a living donor, is required within the first years of life.
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Authors | S Riechardt, M Koch, J Oh, M Fisch |
Journal | Der Urologe. Ausg. A
(Urologe A)
Vol. 56
Issue 7
Pg. 882-886
(Jul 2017)
ISSN: 1433-0563 [Electronic] Germany |
Vernacular Title | Frühe beidseitige Nephrektomie bei Säuglingen mit pränataler ARPKD : Prognoseverbesserung oder unnötiger Aufwand? |
PMID | 28597060
(Publication Type: Journal Article, Review)
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Topics |
- Cesarean Section
- Early Medical Intervention
- Female
- Hemodialysis, Home
- Humans
- Infant
- Infant, Newborn
- Kidney Transplantation
- Nephrectomy
- Peritoneal Dialysis
- Polycystic Kidney, Autosomal Recessive
(diagnosis, mortality, surgery)
- Pregnancy
- Survival Rate
- Waiting Lists
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