Adaptive Optics Scanning Laser Ophthalmoscopy and Multimodal Imaging of Peau D'Orange in Pseudoxanthoma Elasticum.

Abstract

A 41-year-old male with pseudoxanthoma elasticum who presented with progressive vision loss in his left periphery is discussed. Bilateral angioid streaks, optic disc drusen, choroidal neovascularization, and peau d'orange were present. Imaging of the area with peau d'orange with adaptive optics scanning laser ophthalmoscopy and en face optical coherence tomography at Bruch's membrane (BM) revealed a pattern identical to the patches of peau d'orange visible with conventional fundus imaging techniques. These results show that structural abnormalities at the level of BM, likely a result of calcification, correlate with the characteristic "orange peel" pattern known as peau d'orange. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:436-440.].

• Authors: Alex C Onishi, Peter L Nesper, Amani A Fawzi
• Journal: Ophthalmic surgery, lasers & imaging retina (Ophthalmic Surg Lasers Imaging Retina) Vol. 48 Issue 5 Pg. 436-440 (05 01 2017) ISSN: 2325-8179 [Electronic] United States
• PMID: 28499057 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: Copyright 2017, SLACK Incorporated.

Topics

• Adult
• Angioid Streaks (diagnosis, etiology)
• Bruch Membrane (pathology)
• Equipment Design
• Fluorescein Angiography (methods)
• Fundus Oculi
• Humans
• Male
• Multimodal Imaging
• Ophthalmoscopy (methods)
• Optics and Photonics
• Pseudoxanthoma Elasticum (complications, diagnosis)
• Retinal Pigment Epithelium (pathology)
• Tomography, Optical Coherence (methods)