HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Frequency and clinical impact of retained implantable cardioverter defibrillator lead materials in heart transplant recipients.

Abstract
End-stage heart failure patients with implantable cardioverter-defibrillator (ICD) with/without cardiac resynchronization therapy (CRT-D) often require heart transplantation (HTPL) as a last-resort treatment. We aimed to assess the frequency and clinical impact of retained ICD lead materials in HTPL patients. In this retrospective single center study, we examined the clinical records and chest radiographs of patients with ICD and CRT-D who underwent HTPL between January 1992 and July 2014. Of 40 patients with ICD and CRT-D at HTPL, 19 (47.5%) patients had retained ICD lead materials within the central venous system. Retained ICD lead materials following HTPL were more frequently noted in patients with longer implantation durations until HTPL. None of the patients underwent extraction procedures after HTPL. All patients were asymptomatic and did not exhibit significant complications or death related to the retained ICD lead materials. Seven (7/40, 17.5%) patients without any retained ICD lead materials underwent magnetic resonance imaging (MRI) during the follow-up period (median, 29.5 months); none of the patients with retained lead materials were given MRI. Considering the common use of MRI in HTPL patients, further studies on the prophylactic extraction of retained ICD lead materials and safety of MRI in these patients are needed.
AuthorsJun Kim, Jongmin Hwang, Jin Hee Choi, Hyo-In Choi, Min-Seok Kim, Sung-Ho Jung, Gi-Byoung Nam, Kee-Joon Choi, Jae Won Lee, You-Ho Kim, Jae-Joong Kim
JournalPloS one (PLoS One) Vol. 12 Issue 5 Pg. e0176925 ( 2017) ISSN: 1932-6203 [Electronic] United States
PMID28464008 (Publication Type: Journal Article)
Topics
  • Cardiac Resynchronization Therapy
  • Cardiac Resynchronization Therapy Devices (adverse effects)
  • Clinical Protocols
  • Defibrillators, Implantable (adverse effects)
  • Female
  • Follow-Up Studies
  • Foreign Bodies (diagnostic imaging, epidemiology, surgery)
  • Heart Failure (diagnostic imaging, epidemiology, surgery)
  • Heart Transplantation
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Radiography, Thoracic
  • Retrospective Studies
  • Veins (diagnostic imaging)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: