Corneal collagen crosslinking and pigment dispersion syndrome.

Abstract

We describe the case of a keratoconus patient with pigment dispersion syndrome (PDS) who was treated for progressive corneal ectasia with corneal collagen crosslinking (CXL). Pigment dispersion syndrome has been shown to have associated morphologic changes of the corneal endothelium. Corneal CXL has the potential to cause toxicity to the corneal endothelium, and adjacent pigment might increase the likelihood of damage. In this case, the presence of PDS had no detrimental effect on the outcome of treatment, and no complications were observed at 12 months follow-up, indicating that it may be safe to perform corneal CXL in the setting of PDS. This is an important observation as the number of indications for corneal CXL grows.

• Authors: Benjamin R LaHood, Sacha Moore
• Journal: Journal of cataract and refractive surgery (J Cataract Refract Surg) Vol. 43 Issue 3 Pg. 424-425 (03 2017) ISSN: 1873-4502 [Electronic] United States
• PMID: 28410728 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2017 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

Chemical References

• Cross-Linking Reagents
• Riboflavin

Topics

• Cross-Linking Reagents (therapeutic use)
• Endothelium, Corneal
• Glaucoma, Open-Angle (chemically induced)
• Humans
• Keratoconus (drug therapy)
• Riboflavin (therapeutic use)