Proteomic Approaches to Enable Point-of-Care Testing and Personalized Medicine for Psychiatric Disorders.

Abstract

This chapter describes how innovations that are driven by proteomic biomarker techniques can facilitate earlier and better treatment of patients who suffer from psychiatric disorders. The application of new micro-fluidic devices along with miniaturized biosensors and transducers will enable the development of handheld point-of-care testing instruments which can analyse a drop of a blood within the time span of a single visit to the doctor's office. It is anticipated that these approaches will incorporate both biochemical and clinical information, resulting in unique profiles for each test subject. These profiles can in turn be used to drive personalized medicine approaches in this devastating disease area. In addition, smartphone applications (apps) for self-monitoring will see increasing use for improved patient outcomes.

• Authors: Francesca L Guest, Paul C Guest
• Journal: Advances in experimental medicine and biology (Adv Exp Med Biol) Vol. 974 Pg. 363-370 ( 2017) ISSN: 0065-2598 [Print] United States
• PMID: 28353256 (Publication Type: Journal Article, Review)

Chemical References

• Biomarkers
• Reagent Strips

Topics

• Biomarkers (analysis)
• Forecasting
• Gas Chromatography-Mass Spectrometry (instrumentation)
• Humans
• Lab-On-A-Chip Devices
• Mental Disorders (blood, diagnosis)
• Miniaturization
• Mobile Applications
• Point-of-Care Testing (trends)
• Precision Medicine (methods, trends)
• Proteomics (instrumentation, methods, trends)
• Reagent Strips
• Smartphone