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Idelalisib is effective in patients with high-risk follicular lymphoma and early relapse after initial chemoimmunotherapy.

AuthorsAjay K Gopal, Brad S Kahl, Christopher R Flowers, Peter Martin, Stephen M Ansell, Esteban Abella-Dominicis, Brian Koh, Wei Ye, Paul M Barr, Gilles A Salles, Jonathan W Friedberg
JournalBlood (Blood) Vol. 129 Issue 22 Pg. 3037-3039 (06 01 2017) ISSN: 1528-0020 [Electronic] United States
PMID28325864 (Publication Type: Clinical Trial, Phase II, Letter, Multicenter Study, Research Support, Non-U.S. Gov't)
Chemical References
  • Antibodies, Monoclonal, Murine-Derived
  • Purines
  • Quinazolinones
  • R-CHOP protocol
  • Rituximab
  • Vincristine
  • Doxorubicin
  • Cyclophosphamide
  • Prednisone
  • idelalisib
Topics
  • Antibodies, Monoclonal, Murine-Derived (administration & dosage, adverse effects)
  • Antineoplastic Combined Chemotherapy Protocols (administration & dosage, adverse effects)
  • Cyclophosphamide (administration & dosage, adverse effects)
  • Disease-Free Survival
  • Doxorubicin (administration & dosage, adverse effects)
  • Female
  • Humans
  • Lymphoma, Follicular (drug therapy, mortality, pathology)
  • Male
  • Prednisone (administration & dosage, adverse effects)
  • Purines (administration & dosage, adverse effects)
  • Quinazolinones (administration & dosage, adverse effects)
  • Recurrence
  • Rituximab
  • Survival Rate
  • Vincristine (administration & dosage, adverse effects)

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