Punch graft versus follicular hair transplantation in the treatment of stable vitiligo.

Abstract

OBJECTIVE:

To compare the efficacy of follicular hair transplantation and mini punch graft in the treatment of stable vitiligo.

METHODS:

Thirty-two patients with stable vitiligo were included in this comparative study. A single patch from each patient was divided into two halves: one half was treated by punch graft, while the other half was treated by follicular hair transplantation followed by excimer light twice weekly, and the outcome was assessed at 0, 1, 3 and 6 months post operatively by photography and quartile scale.

RESULTS:

At the final visit, the percentage of improvement of vitiligo in punch graft-treated side was significantly higher than that in follicular hair transplantation-treated side (p < 0.05). Also, repigmentation after punch grafting occurred after a mean period of 2.5 ± 0.5 weeks (range, 2-3 weeks), while after follicular hair transplantation, repigmentation occurred after 5.2 ± 1.9 weeks (range, 5-8 weeks) (p < 0.05). Cobblestone appearance was the most common complication after punch graft; it occurred in 29 patients (90%), while no reported side effects occurred after follicular graft technique.

CONCLUSION:

Punch grafting is more effective than follicular grafting in the treatment of stable vitiligo; however, follicular hair transplantation is cosmetically better, so we recommend it in exposed areas as face.

• Authors: Essam-Elden Mohamed Mohamed, Abdel-Khalek Younes, Ahmed Osmand, Refaat Mohamed, Mahmoud Makki, Marwa Younis
• Journal: Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology (J Cosmet Laser Ther) Vol. 19 Issue 5 Pg. 290-293 (Oct 2017) ISSN: 1476-4180 [Electronic] England
• PMID: 28272910 (Publication Type: Comparative Study, Journal Article)

Topics

• Adolescent
• Adult
• Child
• Female
• Hair Follicle (transplantation)
• Humans
• Lasers, Excimer (therapeutic use)
• Male
• Photography
• Skin Pigmentation
• Skin Transplantation (adverse effects, methods)
• Time Factors
• Treatment Outcome
• Vitiligo (surgery)
• Young Adult