Abstract |
Objective: To assess whether preoperative pentazocine can reduce intraoperative hemodynamic changes and postoperative pain. Methods: Fifty patients undergoing laparoscopic cholecystectomy were randomized into two groups. Group P received intravenous 0.5 mg/kg pentazocine 10 min before surgery, and Group C received normal saline as a placebo. A standardized general anesthesia was conducted in all patients. Mean blood pressure (MBP), heart rate (HR), and visual analog scale (VAS) scores at various time points were recorded. The tramadol consumption during the study period was recorded. RESULTS: Group P had lower VAS scores at two, four, and eight hours postoperatively compared with Group C. MBP and HR rose significantly because of pneumoperitoneum within Group C, and no significant changes were detected in MBP and HR within Group P. Tramadol doses given were statistically fewer in Group P. CONCLUSION:
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Authors | Na Wang, Lei Wang, Yang Gao, Honglan Zhou, Jinguo Wang |
Journal | Cureus
(Cureus)
Vol. 8
Issue 12
Pg. e948
(Dec 31 2016)
ISSN: 2168-8184 [Print] United States |
PMID | 28168126
(Publication Type: Journal Article)
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