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Hyper-CVAD + epratuzumab as a salvage regimen for younger patients with relapsed/refractory CD22-positive precursor B-cell acute lymphocytic leukemia.

AuthorsPatrice Chevallier, Sylvain Chantepie, Francoise Huguet, Emmanuel Raffoux, Xavier Thomas, Thibaut Leguay, Tony Marchand, Francoise Isnard, Aude Charbonnier, Sébastien Maury, Maria-Pilar Gallego-Hernanz, Nelly Robillard, Thierry Guillaume, Pierre Peterlin, Alice Garnier, Fanny Rialland, Claire Le Houerou, David M Goldenberg, William A Wegener, Marie-C Béné, Hervé Dombret
JournalHaematologica (Haematologica) Vol. 102 Issue 5 Pg. e184-e186 (05 2017) ISSN: 1592-8721 [Electronic] Italy
PMID28154086 (Publication Type: Letter, Research Support, Non-U.S. Gov't)
Chemical References
  • Antibodies, Monoclonal, Humanized
  • Biomarkers
  • CD22 protein, human
  • Sialic Acid Binding Ig-like Lectin 2
  • epratuzumab
  • Vincristine
  • Dexamethasone
  • Doxorubicin
  • Cyclophosphamide
Topics
  • Adult
  • Antibodies, Monoclonal, Humanized (administration & dosage)
  • Antineoplastic Combined Chemotherapy Protocols (adverse effects, therapeutic use)
  • Biomarkers
  • Cyclophosphamide (adverse effects, therapeutic use)
  • Dexamethasone (adverse effects, therapeutic use)
  • Doxorubicin (adverse effects, therapeutic use)
  • Drug Resistance, Neoplasm
  • Female
  • Humans
  • Male
  • Middle Aged
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma (drug therapy, metabolism, mortality, pathology)
  • Recurrence
  • Retreatment
  • Sialic Acid Binding Ig-like Lectin 2 (metabolism)
  • Treatment Outcome
  • Vincristine (adverse effects, therapeutic use)
  • Young Adult

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