[A Case of Laparoscopic Surgery for Rectal Cancer with Synchronous Lung Metastases after Chemotherapy].

Abstract

A woman in her 70's presented with the predominant complaint of bloody stools. She was diagnosed with rectal cancer, and bilateral lymph node and pulmonary metastases were detected on computed tomography(CT). The patient was diagnosed with cT3N3M1a, cStage IV disease. After undergoing a colostomy, the patient was treated with S-1 plus oxaliplatin (SOX), and bevacizumab(Bev). A second CT scan obtained after completion of 7 courses of chemotherapy revealed that the lung metastases had significantly reduced or disappeared. Approximately 7 months after initial treatment, the patient underwent a laparoscopic Hartmann procedure to remove the tumor. The patient is currently under observation while being administered postoperative adjuvant chemotherapy as an outpatient in our department. There is currently no evidence of the safety of laparoscopic-assisted rectal cancer surgery for first-time Stage IV cases. However, when tumor regression has been achieved with chemotherapy, it may be an effective option.

• Authors: Tatsuya Yoshida, Hajime Morohashi, Daichi Ichinohe, Eri Yoshida, Kensuke Okano, Hayato Nagase, Harue Akasaka, Hiroyuki Jin, Takuya Miura, Yoshiyuki Sakamoto, Kenichi Hakamada
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 43 Issue 12 Pg. 2320-2322 (Nov 2016) ISSN: 0385-0684 [Print] Japan
• PMID: 28133308 (Publication Type: Case Reports, Journal Article)

Chemical References

• Drug Combinations
• Organoplatinum Compounds
• Oxaliplatin
• S 1 (combination)
• Tegafur
• Bevacizumab
• Oxonic Acid

Topics

• Aged
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Bevacizumab (administration & dosage)
• Colostomy
• Drug Combinations
• Female
• Humans
• Laparoscopy
• Lung Neoplasms (drug therapy, secondary)
• Organoplatinum Compounds (administration & dosage)
• Oxaliplatin
• Oxonic Acid (administration & dosage)
• Rectal Neoplasms (drug therapy, pathology, surgery)
• Tegafur (administration & dosage)