[A Case of Primary Splenic Inflammatory Myofibroblastic Tumor].

Abstract

Inflammatory myofibroblastic tumor(IMT)is a rare neoplasm. IMTs are found in a number of locations throughout the body, but splenic involvement is uncommon. One case of splenic IMT is described. A 42-year-old woman presented with anterior chest pain and was found to have a splenic mass by computed tomography(CT). Fluorine-18-FDG-PET showed no FDG accumulation in the spleen. Magnetic resonance imaging(MRI)at 6 months follow-up showed an increase in the size of the tumor. We performed splenectomy for a suspected malignant tumor. The surgical specimen was a gray-white mass in the spleen. The mass was histopathologically diagnosed as primary splenic IMT because it consisted of desmin- and SMA-positive spindle-shaped cells with various inflammatory cells. In Japan, only 6 cases(including this case)of primary splenic IMT have been reported. Surgery is the only curative approach, but recurrences occur in around 5% of cases of pulmonary IMT, and around 25% of cases of extrapulmonary IMT. This patient needs to be carefully followed up.

• Authors: Yosuke Atsumi, Masaaki Murakawa, Koichiro Yamaoku, Toru Aoyama, Amane Kanazawa, Akio Higuchi, Manabu Shiozawa, Satoshi Kobayashi, Makoto Ueno, Manabu Morimoto, Kota Washimi, Tomoyuki Yokose, Naoto Yamamoto, Takashi Oshima, Norio Yukawa, Takaki Yoshikawa, Yasushi Rino, Munetaka Masuda, Soichiro Morinaga
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 43 Issue 12 Pg. 2268-2270 (Nov 2016) ISSN: 0385-0684 [Print] Japan
• PMID: 28133291 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Female
• Humans
• Magnetic Resonance Imaging
• Multimodal Imaging
• Neoplasms, Muscle Tissue (diagnostic imaging, surgery)
• Positron-Emission Tomography
• Splenectomy
• Splenic Neoplasms (diagnostic imaging, surgery)
• Tomography, X-Ray Computed