[Innovation of bisphosphonates for improvement of adherence.]

Abstract

Bisphosphonates are standard medicine for treatment of osteoporosis, and have been inovated to overcome complicated rules for their appropriate administration or their poor intestinal absorption. Not only weekly but also monthly oral bisphosphonates have been available. Furthermore, we are now allowed to choose intravenous administration of bisphosphonates for osteorporosis. Good persistance and adherence is another critical and essential issue to be solved to achive the aim of osteoprosis treatment with bisphosphonates. Variable formulations of bisphosphonate are now able to bring patients closer to a goal of reduction in fragile fracture due to osteoporosis.

• Authors: Yasuhiro Takeuchi
• Journal: Clinical calcium (Clin Calcium) 2017 Vol. 27 Issue 2 Pg. 197-202 ISSN: 0917-5857 [Print] Japan
• PMID: 28123121 (Publication Type: Journal Article, Review)

Chemical References

• Bone Density Conservation Agents
• Diphosphonates

Topics

• Bone Density Conservation Agents (administration & dosage, adverse effects, therapeutic use)
• Diphosphonates (administration & dosage, adverse effects, therapeutic use)
• Humans
• Kidney Diseases (chemically induced)
• Medication Adherence
• Osteoporosis (prevention & control)
• Osteoporotic Fractures (prevention & control)