HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

After microvascular decompression to treat trigeminal neuralgia, both immediate pain relief and recurrence rates are higher in patients with arterial compression than with venous compression.

Abstract
We explored differences in postoperative pain relief achieved through decompression of the trigeminal nerve compressed by arteries and veins. Clinical characteristics, intraoperative findings, and postoperative curative effects were analyzed in 72 patients with trigeminal neuralgia who were treated by microvascular decompression. The patients were divided into arterial and venous compression groups based on intraoperative findings. Surgical curative effects included immediate relief, delayed relief, obvious reduction, and invalid result. Among the 40 patients in the arterial compression group, 32 had immediate pain relief of pain (80.0%), 5 cases had delayed relief (12.5%), and 3 cases had an obvious reduction (7.5%). In the venous compression group, 12 patients had immediate relief of pain (37.5%), 13 cases had delayed relief (40.6%), and 7 cases had an obvious reduction (21.9%). During 2-year follow-up period, 6 patients in the arterial compression group experienced recurrence of trigeminal neuralgia, but there were no recurrences in the venous compression group. Simple artery compression was followed by early relief of trigeminal neuralgia more often than simple venous compression. However, the trigeminal neuralgia recurrence rate was higher in the artery compression group than in the venous compression group.
AuthorsLei Shi, Xiaoyan Gu, Guan Sun, Jun Guo, Xin Lin, Shuguang Zhang, Chunfa Qian
JournalOncotarget (Oncotarget) Vol. 8 Issue 27 Pg. 44819-44823 (Jul 04 2017) ISSN: 1949-2553 [Electronic] United States
PMID28122347 (Publication Type: Journal Article)
Topics
  • Adult
  • Aged
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Microvascular Decompression Surgery (adverse effects, methods)
  • Middle Aged
  • Pain Management (adverse effects, methods)
  • Postoperative Complications
  • Recurrence
  • Treatment Outcome
  • Trigeminal Neuralgia (therapy)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: