A Pilot Study of Vela Laser for En Bloc Resection of Papillary Bladder Cancer.

Abstract

INTRODUCTION:

The present study evaluated the safety and efficacy of the Vela laser for en bloc resection of papillary bladder tumors.

MATERIALS AND METHODS:

From January 2013 to August 2014, 38 patients underwent en bloc resection with the Vela laser and a 26F continuous flow resectoscope or 18F flexible cystoscope. Random cold forceps biopsy samples were also taken. The total operation time, pathologic result, and intraoperative and postoperative complications were recorded. Each patient was followed up for ≥ 1 year.

RESULTS:

The average total operation time was 23 minutes. The en bloc resection of all tumors was successful, with 2 cases located at the bladder dome requiring the use of a flexible cystoscope for better management. No complications occurred during or after surgery. All resected tumors were intact with the detrusor muscle layer and architecture available for pathologic evaluation. One patient with stage T2b tumor underwent laparoscopic cystectomy 1 week after the initial surgery. At a median follow-up period of 21.8 months, the recurrence rate at 12 months was 21.6% (8 of 37).

CONCLUSION:

The results of our study have shown that the Vela laser is an effective, feasible, and safe thulium laser for en bloc bladder tumor resection. It was associated with negligible complications and allows accurate pathologic evaluation. The Vela laser can serve as an alternative treatment method for nonmuscle-invasive bladder cancer or infiltrating tumor.

• Authors: Zhensheng Zhang, Shuxiong Zeng, Junjie Zhao, Xin Lu, Weidong Xu, Chong Ma, Yang Wang, Xin Chen, Gaozhen Jia, Tie Zhou, Yinghao Sun, Chuanliang Xu
• Journal: Clinical genitourinary cancer (Clin Genitourin Cancer) Vol. 15 Issue 3 Pg. e311-e314 (06 2017) ISSN: 1938-0682 [Electronic] United States
• PMID: 28110833 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2016 Elsevier Inc. All rights reserved.

Topics

• Adult
• Aged
• Carcinoma, Papillary (pathology, surgery)
• Cystoscopy (instrumentation)
• Female
• Humans
• Lasers, Solid-State (therapeutic use)
• Male
• Middle Aged
• Neoplasm Staging
• Operative Time
• Pilot Projects
• Treatment Outcome
• Urinary Bladder Neoplasms (pathology, surgery)