Hyponatremia in an Elderly Patient due to Isolated Hypoaldosteronism Occurring after Licorice Withdrawal.

Abstract

Hyponatremia is one of the most common electrolyte disorders encountered in the elderly. We present the case of an 81-year-old man who developed hyponatremia due to isolated hypoaldosteronism occurring after licorice withdrawal. He had severe hypokalemia with hypertension and was diagnosed with pseudoaldosteronism. He had been taking a very small dose of licorice as a mouth refresher since his early adulthood. Five months after licorice withdrawal, he developed hypovolemic hyponatremia, which was resolved with administration of fludrocortisone acetate. Our experience with this case suggests that isolated hypoaldosteronism occurring after licorice withdrawal should be considered as a potential cause of hyponatremia in elderly patients.

• Authors: Yuji Hataya, Akifumi Oba, Takafumi Yamashita, Yasato Komatsu
• Journal: Internal medicine (Tokyo, Japan) (Intern Med) Vol. 56 Issue 2 Pg. 175-179 ( 2017) ISSN: 1349-7235 [Electronic] Japan
• PMID: 28090048 (Publication Type: Case Reports, Journal Article)

Chemical References

• Drugs, Chinese Herbal
• Mouthwashes
• Fludrocortisone
• fludrocortisone acetate

Topics

• Aged, 80 and over
• Diagnosis, Differential
• Drugs, Chinese Herbal
• Fludrocortisone (analogs & derivatives, therapeutic use)
• Glycyrrhiza
• Humans
• Hypoaldosteronism (blood, complications, diagnosis, drug therapy)
• Hyponatremia (blood, complications, diagnosis, drug therapy)
• Male
• Mouthwashes