Malignant Transformation of Hepatocellular Adenoma.

Abstract

The patient was a 20-year-old male in whom a hepatic hypervascular mass accompanied by intratumoral hemorrhage was detected on examination for epigastric pain. Based on the enlargement of the mass and diagnostic imaging, hepatocellular adenoma (HCA) was suspected and hepatectomy was performed. The lesion was diagnosed as malignant transformation of β-catenin-activated HCA. There are only few reports of cases with malignant transformation of HCA in Japan; it is necessary to accumulate cases to investigate it.

• Authors: Wing Yee Kwok, Satoru Hagiwara, Naoshi Nishida, Tomohiro Watanabe, Toshiharu Sakurai, Hiroshi Ida, Yasunori Minami, Masahiro Takita, Tomohiro Minami, Mina Iwanishi, Hirokazu Chishina, Masashi Kono, Kazuomi Ueshima, Yoriaki Komeda, Tadaaki Arizumi, Eisuke Enoki, Takuya Nakai, Tsutomu Kumabe, Osamu Nakashima, Fukuo Kondo, Masatoshi Kudo
• Journal: Oncology (Oncology) Vol. 92 Suppl 1 Pg. 16-28 ( 2017) ISSN: 1423-0232 [Electronic] Switzerland
• PMID: 27988517 (Publication Type: Case Reports, Journal Article)
• Copyright: © 2016 S. Karger AG, Basel.

Topics

• Adenoma, Liver Cell (diagnostic imaging, pathology, surgery)
• Adult
• Cell Transformation, Neoplastic (pathology)
• Humans
• Liver Neoplasms (diagnostic imaging, pathology, surgery)
• Male
• Young Adult