Outdoor Air Pollution and Pterygium in Korea.

Abstract

We investigated relationships between outdoor air pollution and pterygium in Korean adults. This study includes 23,276 adults in population-based cross-sectional data using the Korea National Health and Nutrition Examination Survey 2008-2011. Pterygium was assessed using slit lamp biomicroscopy. Air pollution data (humidity, particulate matter with aerodynamic diameter less than 10 μm [PM₁₀], ozone [O₃], nitrogen dioxide [NO₂], and sulfur dioxide levels [SO₂]) for 2 years preceding the ocular examinations were acquired. Associations of multiple air pollutants with pterygium or pterygium recurrence after surgery were examined using multivariate logistic models, after adjusting for several covariates. Distributed lag models were additionally used for estimating cumulative effects of air pollution on pterygium. None of air pollution factors was significantly associated with pterygium or pterygium recurrence (each P > 0.05). Distributed lag models also showed that air pollution factors were not associated with pterygium or pterygium recurrence in 0-to-2 year lags (each P > 0.05). However, primary pterygium showed a weak association with PM10 after adjusting for covariates (odds ratio [OR] 1.23; [per 5 μg/m³ PM₁₀ increase]; P = 0.023). Aging, male sex, and greater sun exposure were associated with pterygium, while higher education level and myopia were negatively associated with pterygium (each P ≤ 0.001). Male sex and myopia were negatively associated with pterygium recurrence (each P < 0.05). In conclusion, exposure to higher PM10 levels was associated with primary pterygium, although this study observed no significant association between air pollution and overall pterygium or pterygium recurrence in Korean adults.

• Authors: Ki Woong Lee, Yoon Hyeong Choi, Sung Ha Hwang, Hae Jung Paik, Mee Kum Kim, Won Ryang Wee, Dong Hyun Kim
• Journal: Journal of Korean medical science (J Korean Med Sci) Vol. 32 Issue 1 Pg. 143-150 (Jan 2017) ISSN: 1598-6357 [Electronic] Korea (South)
• PMID: 27914144 (Publication Type: Journal Article)

Chemical References

• Air Pollutants
• Particulate Matter
• Sulfur Dioxide
• Ozone
• Nitrogen Dioxide

Topics

• Adult
• Aged
• Air Pollutants (analysis, toxicity)
• Cross-Sectional Studies
• Female
• Humans
• Humidity
• Logistic Models
• Male
• Middle Aged
• Myopia (etiology)
• Nitrogen Dioxide (analysis)
• Nutrition Surveys
• Odds Ratio
• Ozone (analysis)
• Particulate Matter (analysis)
• Pterygium (diagnosis, epidemiology, etiology)
• Recurrence
• Republic of Korea (epidemiology)
• Sex Factors
• Sulfur Dioxide (analysis)
• Young Adult