Outer Retinal and Choroidal Evaluation in Multiple Evanescent White Dot Syndrome (MEWDS): An Enhanced Depth Imaging Optical Coherence Tomography Study.

Abstract

PURPOSE:

To perform an analysis of optical coherence tomography (OCT) abnormalities in patients with MEWDS, during the acute and recovery stages, using enhanced depth imaging-OCT (EDI-OCT).

METHODS:

A retrospective case series of five patients with MEWDS was included. EDI-OCT imaging was evaluated to detect retinal and choroidal features.

RESULTS:

In the acute phase, focal impairment of the ellipsoid zone and external limiting membrane, hyperreflective dots in the inner choroid, and full-thickness increase of the choroidal profile were observed in the affected eye; disappearance of these findings and restoration of the choroidal thickness (p = 0.046) was appreciated in the recovery phase. No OCT abnormalities were assessed in the unaffected eye.

CONCLUSIONS:

EDI-OCT revealed transient outer retinal layer changes and inner choroidal hyperreflective dots. A transient increased thickness of the whole choroid was also identified. This might confirm a short-lasting inflammatory involvement of the whole choroidal tissue in the active phase of MEWDS.

• Authors: Tito Fiore, Barbara Iaccheri, Alessio Cerquaglia, Marco Lupidi, Giovanni Torroni, Daniela Fruttini, Carlo Cagini
• Journal: Ocular immunology and inflammation (Ocul Immunol Inflamm) Vol. 26 Issue 3 Pg. 428-434 ( 2018) ISSN: 1744-5078 [Electronic] England
• PMID: 27726467 (Publication Type: Journal Article)

Topics

• Acute Disease
• Adult
• Choroid Diseases (diagnostic imaging)
• Female
• Humans
• Male
• Middle Aged
• Retinal Diseases (diagnostic imaging)
• Retinal Pigment Epithelium (diagnostic imaging)
• Retrospective Studies
• Syndrome
• Tomography, Optical Coherence (methods)
• Young Adult