Abstract |
In 498 subjects (205 normolipidemics and 293 hyperlipidemics) of both sexes, the cholesterol content of high density lipoprotein (HDL) subfractions has been determined. The serum concentration of total HDL-cholesterol appears to be more strictly related to the cholesterol content of HDL2 than to that of HDL3. This latter one, however, gives a contribution to the variability of HDL-cholesterol so that the value of HDL-cholesterol cannot be assumed as a reliable estimate of the serum level of the more anti-atherogenic HDL2 subfraction. The cholesterol content of HDL and its subfractions is higher in women than in men and decreases with increasing serum VLDL-cholesterol level and body weight. Both HDL2- and HDL3-cholesterol appear to largely depend from the metabolism of triglyceride-rich lipoproteins in accordance with the data of experimental studies.
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Authors | D Sommariva, A Branchi, D Bonfiglioli, M Tirrito, E Cabrini, C Pini, L Scandiani, A Rovellini, A Fasoli |
Journal | La Ricerca in clinica e in laboratorio
(Ric Clin Lab)
1989 Apr-Jun
Vol. 19
Issue 2
Pg. 165-72
ISSN: 0390-5748 [Print] Italy |
PMID | 2772489
(Publication Type: Journal Article)
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Chemical References |
- Cholesterol, HDL
- Cholesterol, LDL
- Cholesterol, VLDL
- Cholesterol
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Topics |
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Body Weight
- Cholesterol
(blood)
- Cholesterol, HDL
(blood, classification)
- Cholesterol, LDL
(blood)
- Cholesterol, VLDL
(blood)
- Female
- Humans
- Hyperlipidemias
(blood)
- Male
- Middle Aged
- Regression Analysis
- Sex Factors
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