Abstract | INTRODUCTION: AIM: To estimate the incidence of VTE from the standard feminizing CSHTs used in the United States. METHODS: A retrospective chart review of transgender women who had been prescribed oral estradiol at a District of Columbia community health center was performed. MAIN OUTCOME MEASURE: RESULTS: From January 1, 2008 through March 31, 2016, 676 transgender women received oral estradiol-based CSHT for a total of 1,286 years of hormone treatment and a mean of 1.9 years of CSHT per patient. Only one individual, or 0.15% of the population, sustained a VTE, for an incidence of 7.8 events per 10,000 person-years. CONCLUSION: There was a low incidence of VTE in this population of transgender women receiving oral estradiol.
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Authors | Justin D Arnold, Eleanor P Sarkodie, Megan E Coleman, Deborah A Goldstein |
Journal | The journal of sexual medicine
(J Sex Med)
Vol. 13
Issue 11
Pg. 1773-1777
(11 2016)
ISSN: 1743-6109 [Electronic] Netherlands |
PMID | 27671969
(Publication Type: Journal Article)
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Copyright | Copyright © 2016 International Society for Sexual Medicine. Published by Elsevier Inc. All rights reserved. |
Chemical References |
- Androgen Antagonists
- Estrogens
- Gonadal Steroid Hormones
- Mineralocorticoid Receptor Antagonists
- Spironolactone
- Cyproterone Acetate
- Estradiol
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Topics |
- Administration, Oral
- Adult
- Androgen Antagonists
(administration & dosage)
- Cyproterone Acetate
(adverse effects)
- District of Columbia
(epidemiology)
- Estradiol
(administration & dosage, adverse effects)
- Estrogens
(administration & dosage, adverse effects)
- Europe
- Female
- Gender Identity
- Gonadal Steroid Hormones
(administration & dosage, adverse effects)
- Humans
- Incidence
- Male
- Middle Aged
- Mineralocorticoid Receptor Antagonists
(administration & dosage, adverse effects)
- Retrospective Studies
- Risk Factors
- Spironolactone
(administration & dosage, adverse effects)
- Transgender Persons
(psychology)
- Transsexualism
(complications, epidemiology, psychology)
- Venous Thrombosis
(chemically induced, epidemiology)
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