Exposure to phthalates in house dust and associated allergies in children aged 6-12years.

Abstract

Phthalates are widely used as plasticizers in household products. Several studies have reported an association between phthalate exposure and an increased risk of allergies. The present study estimated phthalate exposure in children aged 6-12years and assessed potential correlations with allergies. House dust samples were collected from floors and multi-surface objects >35cm above the floor. Urine samples were collected from the first morning void of the day. Daily phthalate intake (DIdust and DI) was estimated using both house dust and urinary metabolite concentrations. Exposure to di-2-ethylhexyl phthalate (DEHP) in floor dust was associated with parental-reported rhino-conjunctivitis. After stratification by gender, this trend was found to only occur in boys. Furthermore, urinary mono-isobutyl phthalate was inversely associated with parental-reported wheeze in boys. DIdust of benzyl butyl phthalate (BBzP) and DEHP were significantly correlated with DI_BBzP and DI_DEHP, respectively. These correlations were stronger with floor than with multi-surface dust. Our results suggest that, among Japanese children, house dust from low surfaces, such as living room floors, might play a meaningful role in the indoor environmental exposure pathway for BBzP and DEHP.

• Authors: Yu Ait Bamai, Atsuko Araki, Toshio Kawai, Tazuru Tsuboi, Ikue Saito, Eiji Yoshioka, Shi Cong, Reiko Kishi
• Journal: Environment international (Environ Int) Vol. 96 Pg. 16-23 (Nov 2016) ISSN: 1873-6750 [Electronic] Netherlands
• PMID: 27588698 (Publication Type: Journal Article)
• Copyright: Copyright © 2016 Elsevier Ltd. All rights reserved.

Chemical References

• Dust
• Environmental Pollutants
• Phthalic Acids
• Plasticizers
• mono-isobutyl phthalate
• phthalic acid
• Diethylhexyl Phthalate
• butylbenzyl phthalate

Topics

• Child
• Dermatitis, Atopic (epidemiology, etiology)
• Diethylhexyl Phthalate
• Dust (analysis)
• Environmental Exposure (adverse effects, analysis)
• Environmental Pollutants (adverse effects, analysis, immunology)
• Female
• Floors and Floorcoverings
• Household Products
• Humans
• Hypersensitivity
• Japan (epidemiology)
• Male
• Nose
• Parents
• Phthalic Acids (immunology, urine)
• Plasticizers
• Respiratory Hypersensitivity (epidemiology, etiology)
• Respiratory Sounds