Abstract | INTRODUCTION:
Buprenorphine is a semi-synthetic derivative of thebaine; its low concentration is sufficient to provide effective pain relief. AIM: MATERIALS AND METHODS: After ethical approval and taking informed consent from the patients, they were randomized into three groups ( n=30 in each group) using a computer generated random number table. Group A: placebo patch; Group B: buprenorphine (10mg) patch and Group C: buprenorphine (20mg) patch. Haemodynamic and analgesic effects were compared by using analysis of variance (ANOVA) followed by Turkey's post hoc test. The proportion of side effects was compared using the Chi-square test. RESULTS: Haemodynamic changes were not statistically different in all the three groups A, B and C, whereas at the end of surgery VAS score of Group A subjects was significantly higher (4.93±0.98) as compared to Group B (1.73±0.64) and Group C (1.40±0.50). On 2(nd) postoperative day, no pain was reported by the Group C patients and on 4(th) day after surgery, no pain was reported by Group B patients. CONCLUSION:
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Authors | Santosh Kumar, Ajay Kumar Chaudhary, Prithvi Kumar Singh, Reetu Verma, Girish Chandra, Vinod Kumar Bhatia, Dinesh Singh, Jaishri Bogra |
Journal | Journal of clinical and diagnostic research : JCDR
(J Clin Diagn Res)
Vol. 10
Issue 6
Pg. UC05-8
(Jun 2016)
ISSN: 2249-782X [Print] India |
PMID | 27504383
(Publication Type: Journal Article)
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