Abstract | OBJECTIVE: To improve clinical outcomes, parenteral nutrition, standard enteral nutrition and immuno-enhanced nutrition are widely used in the gastrointestinal tumor patients undergoing surgery, but the optimal management of postoperative nutrition support remains uncertain. METHODS: We systematically searched the PUBMED, EMBASE and CNKI to identify latent studies which the effects of standard EN compared with PN or IEN on gastrointestinal tumor patients until the end of November, 2015. The quality of included trials was assessed according to the handbook for Cochrane reviewer. Statistical analysis was carried out by RevMan5.1 software. RESULTS: 30 randomized controlled trials containing 3854 patients were contained in our meta-analysis, the results indicated that postoperative SEN could absolutely reduce the incidence of postoperative infectious (P < 0.00001) and non-infectious complications (P = 0.0003), together with its positive effect on the length of hospital stay (P < 0.00001). Additionally, enteral nutrition enhanced with immune stimulation was confirmed to be better, with a significant difference between groups in terms of total infectious (P < 0.00001) and non-infectious complications (P = 0.04), and IEN could also significantly shorten the length of hospital stay (P < 0.00001). CONCLUSION:
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Authors | Xia Yan, Fu-Xiang Zhou, Tian Lan, Hui Xu, Xiao-Xi Yang, Cong-Hua Xie, Jing Dai, Zhen-Ming Fu, Yan Gao, Lu-Lu Chen |
Journal | Clinical nutrition (Edinburgh, Scotland)
(Clin Nutr)
Vol. 36
Issue 3
Pg. 710-721
(06 2017)
ISSN: 1532-1983 [Electronic] England |
PMID | 27452745
(Publication Type: Journal Article, Meta-Analysis, Review, Systematic Review)
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Copyright | Copyright © 2016 The Author(s). Published by Elsevier Ltd.. All rights reserved. |
Topics |
- Enteral Nutrition
- Gastrointestinal Neoplasms
(therapy)
- Humans
- Parenteral Nutrition
- Postoperative Period
- Randomized Controlled Trials as Topic
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