Advanced gastric cancer: a new combined surgical and oncological approach.

Abstract

Forty-two patients with advanced gastric carcinoma underwent chemotherapy in accordance with the FAMTX protocol. Complete tumor remission was achieved in 7%, and partial remission in 29% of the patients. In this group 6 patients (tumor stage: T3-4, N 2-3, M X-1) underwent a second-look operation after chemotherapy either to confirm the complete remission or the resect the remaining tumor mass. The mean follow-up time of these 6 patients is 22 (8-55) months; 4 are still in complete remission 8 to 55 months after the first operation. It is concluded that even in advanced stages of gastric carcinomas a more aggressive approach involving a combination of surgical and chemotherapeutic treatment improves the survival time of these patients.

• Authors: B Kremer, D Henne-Bruns, H J Weh, T Effenberger
• Journal: Hepato-gastroenterology (Hepatogastroenterology) Vol. 36 Issue 1 Pg. 23-6 (Feb 1989) ISSN: 0172-6390 [Print] Greece
• PMID: 2744710 (Publication Type: Case Reports, Journal Article)

Chemical References

• Etoposide
• Doxorubicin
• Cisplatin
• Fluorouracil
• Methotrexate

Topics

• Adult
• Aged
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Carcinoma (therapy)
• Cisplatin (administration & dosage)
• Combined Modality Therapy
• Doxorubicin (administration & dosage)
• Etoposide (administration & dosage)
• Female
• Fluorouracil (administration & dosage)
• Follow-Up Studies
• Gastrectomy
• Humans
• Male
• Methotrexate (administration & dosage)
• Middle Aged
• Reoperation
• Stomach Neoplasms (therapy)