Congenital Dyserythropoietic Anemia Type 1: Report of One Patient and Analysis of Previously Reported Patients Treated with Interferon Alpha.

Abstract

Congenital dyserythropoietic anemias are a rare group of inherited anemias characterized by ineffective erythropoiesis and distinct morphological abnormalities in the erythroblasts. Interferon alpha has been shown to be effective in type 1 congenital dyserythropoietic anemia but the optimal duration of therapy is undefined. We present here a 32-years-old female patient diagnosed with type 1 congenital dyserythropoietic anemia precipitated by pregnancy and treated successfully with a short course of interferon alpha resulting in a durable response. A literature search including PubMed database on previously published articles regarding congenital dyserythropoietic anemia type 1 patients treated with interferon is conducted.

• Authors: Ayse Salihoglu, Tugrul Elverdi, Ahmet Emre Eskazan, Deniz Eyice, Isil Bavunoglu, Muhlis Cem Ar, Seniz Ongoren, Elif Guzel, Zafer Baslar, Aydin Tunckale, Nukhet Tuzuner, Teoman Soysal
• Journal: Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion (Indian J Hematol Blood Transfus) Vol. 32 Issue Suppl 1 Pg. 272-7 (Jun 2016) ISSN: 0971-4502 [Print] India
• PMID: 27408411 (Publication Type: Case Reports)