Influence of Posterior Fossa Volume on Clinical Outcomes After Vestibular Schwannoma Resection.

Abstract

OBJECTIVES:

To determine the influence of posterior fossa dimensions on surgical outcomes after vestibular schwannoma management.

STUDY DESIGN:

Retrospective chart review.

SETTING:

Tertiary care academic medical center.

PATIENTS:

Patients with sporadic vestibular schwannomas who underwent surgical resection via retrosigmoid or translabyrinthine techniques.

INTERVENTIONS:

Diagnostic.

MAIN OUTCOME MEASURES:

One and two-way analysis of variance (ANOVAs) of the cohort based on volumetric and clinical outcome groupings.

RESULTS:

A total of 95 patients were identified. A one-way ANOVA looking at the entire cohort of patients showed that outcomes like surgical time (p < 0.001) and whether a Good Outcome (House-Brackmann score of 1 or 2, no complications, and a complete resection) was achieved (p = 0.009) correlated very well with preoperative tumor volume, but not with posterior fossa volume (p = 0.412 and p = 0.345, respectively). However, in medium sized tumors, House-Brackmann group was correlated with posterior fossa volume (p = 0.032).

CONCLUSIONS:

The present data suggest a small effect of posterior fossa size on some clinical outcomes in medium sized vestibular schwannomas.

• Authors: Robert J Macielak, Michael S Harris, Claudia F Kirsch, Luciano M Prevedello, Oliver F Adunka
• Journal: Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology (Otol Neurotol) Vol. 37 Issue 8 Pg. 1155-61 (09 2016) ISSN: 1537-4505 [Electronic] United States
• PMID: 27362739 (Publication Type: Journal Article)

Topics

• Adult
• Aged
• Female
• Humans
• Male
• Middle Aged
• Neuroma, Acoustic (surgery)
• Postoperative Complications (etiology)
• Retrospective Studies
• Skull (anatomy & histology)