Eligibility Criteria for Deep Brain Stimulation in Parkinson's Disease, Tremor, and Dystonia.

Abstract

In this review, the available evidence to guide clinicians regarding eligibility for deep brain stimulation (DBS) in the main conditions in which these forms of therapy are generally indicated-Parkinson's disease (PD), tremor, and dystonia-is presented. In general, the literature shows that DBS is effective for PD, essential tremor, and idiopathic dystonia. In these cases, key points in patient selection must include the level of disability and inability to manage symptoms using the best available medical therapy. Results are, however, still not optimal when dealing with other aetiologies, such as secondary tremors and symptomatic dystonia. Also, in PD, issues such as age and neuropsychiatric profile are still debatable parameters. Overall, currently available literature is able to guide physicians on basic aspects of patient selection and indications for DBS; however, a few points are still debatable and controversial. These issues should be refined and clarified in future studies.

• Authors: Renato P Munhoz, Marina Picillo, Susan H Fox, Veronica Bruno, Michel Panisset, Christopher R Honey, Alfonso Fasano
• Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques (Can J Neurol Sci) Vol. 43 Issue 4 Pg. 462-71 (Jul 2016) ISSN: 0317-1671 [Print] England
• PMID: 27139127 (Publication Type: Journal Article, Review)

Topics

• Deep Brain Stimulation (methods, standards)
• Dystonia (therapy)
• Humans
• Parkinson Disease (therapy)
• Tremor (therapy)